Increasing urbanization has led to problems. Cities are centers of civilization and culture.

A. Although increasing urbanization has led to problems, but cities are centers of civilization and culture.

B. Despite increasing urbanization has led to problems, but cities are centers of civilization and culture.

C. In spite of increasing urbanization has led to problems, yet cities are centers of civilization and culture.

D. Though increasing urbanization has led to problems, cities are centers of civilization and culture.